Material Safety Data Sheet

Realgar

MSDS Number 450-20
Section 1: Product and Company Information
Product Name(s) Realgar
Product Number(s) 450-20
Company Natural Pigments LLC
PO Box 112
Willits, CA 95490
United States of America
Technical Phone 707-459-9998
Fax 408-516-9442
Section 2: Composition / Information on Ingredients
Product Name Realgar
Synonyms eolite, realgarite, red arsenic, red orpiment, rejalgar, risigallo, risigallum, ruby sulfur, ruby sulphur, sandaracha
Component Name CAS No. % Composition Range OSHA PEL mg/m3 ACGIH TLV mg/m3 NIOSH mg/m3
Chemical Formula     TWA STEL TWA STEL IDLH (as Arsenic)
Arsenic sulfide
As4S4
 1303-33-9 Varies 101 N.E.2 2 N.E. 5
1) Final PELs as listed under Arsenic, inorganic compounds. Cancer hazard - see 29 CFR 1 910.1018. 2) N.E. = None Established
Section 3: Hazards Identification
Effects of Exposure Acute arsenic poisoning (from ingestion) results in marked irritation of the stomach and intestines with nausea, vomiting and diarrh ea. In severe cases the vomitus and stoo ls are bloody and the patient goes into collapse and shock with weak, rapid pulse, cold sweats, coma and death. Chronic arsenic poisoning (from ingestion or inhalation) may disturb the digestive system with symptoms of loss of appetite, cramps, nausea, constipation or diarrhea. Liver damage may occur causing jaundice. May disturb blood, kidneys and nervous system. May cause itching, pigmentation and cancer of the skin. Carcinogen of skin, lungs, liver, mouth, esophagus, larynx, bladder and paranasal sinus.
Inhalation
Acute Health Effects Arsenic sulfide is highly irritating to the respiratory tract and may cause pulmonary edema. Exposure to high concentrations affects the central nervous system and may be fatal. Arsenic compounds can cause lung cancer. May be corrosive due to evolutions of arsenic gas on contact with moisture.
Chronic Health Effects Arsenic poisoning may disturb the digestive system with symptoms of loss of appetite, cramps, nausea, constipation or diarrhea. Liver damage may occur causing jaundice. May disturb blood, kidneys and nervous system.
Aggravation of
Pre-existing Conditions		 Medical conditions that may be aggravated by exposure: Any previously existing lung or pulmonary condition.
Ingestion
Acute Health Effects Arsenic poisoning results in marked irritation of the stomach and intestines with nausea, vomiting and diarrhea. In severe cases the vomitus and stools are bloody and the patient goes into collapse and shock with weak, rapid pulse, cold sweats, coma and death.
Chronic Health Effects No information available
Aggravation of
Pre-existing Conditions		 Medical conditions that may be aggravated by exposure: None anticipated.
Eye Contact
Acute Health Effects Arsenic sulfide is highly irritating to eyes and can cause conjunctivitis.
Chronic Health Effects The temporary effects of eye contact or obscured vision due to excessive airborne concentrations may directly impair an individual's ability to locate emergency exits and/or eyewash stations to receive first aid.
Aggravation of
Pre-existing Conditions		 Medical conditions that may be aggravated by exposure: None anticipated.
Skin Contact
Acute Health Effects Arsenic compounds can cause itching, pigmentation and cancer of the skin. May be corrosive due to evolution of arsenic acid contact with moisture.
Chronic Health Effects May cause itching, pigmentation and cancer of the skin. Carcinogen of skin, lungs, liver, mouth, esophagus, larynx, bladder and paranasal sinus.
Aggravation of
Pre-existing Conditions		 Medical conditions that may be aggravated by exposure: None anticipated.
  Health effects described above are based on published scientific information available for review, and evaluated on behalf of this product. Actual signs and symptoms experienced may vary due to conditions at the time of exposure.
Section 4: First Aid Measures
After Inhalation Remove to fresh air. If conscious, have victim clear nasal passages. Restore breathing (e.g., artificial respiration, CPR). Do NOT use mouth-to-mouth resuscitation. Seek medical attention, as necessary, if symptoms develop or persist.
After Skin Contact Brush off skin and wash area with soap and water. Wash clothing before reuse. Call a physician, if irritation occurs.
After Eye Contact Holding eyelids open, do not allow victim to rub their eyes. Gently flush eyes for 15 minutes with large quantities of water. Seek medical attention if irritation develops or persists.
After Ingestion Never give anything by mouth to an unconscious person. If victim is conscious and alert, give 2 to 4 cups of milk or water, but DO NOT induce vomiting. Seek medical attention immediately.
Section 5: Fire Fighting Measures
Fire Not considered to be a fire hazard. Not flammable.
Explosion Not considered to be an explosion hazard.
Flash Points Not applicable
Auto-Ignition Not applicable
Flammable Limits Not applicable
Extinguishing Media Do NOT get water inside containers. Do NOT use straight streams of water. For small fires, use dry chemical, carbon dioxide, or water spray. Cool containers with flooding quantities of water until well after fire is out. For large fires, use water spray, fog or regular foam.
Special Fire Fighting Procedure As part of responding to any fire, firefighters should wear full turnout gear with a positive pressure demand mode Self-Contained Breathing Apparatus (SCBA). Contain all fire suppression run-off.
Hazardous Thermal
Decomposition Byproducts		 This product, when heated to decomposition temperature, may emit toxic fumes of arsenic gas, arsenic oxide and hydrogen sulfide.
Fire/Explosion Hazards Incompatible with strong oxidizers, acid or acid fumes, hydrogen peroxide, and active metals, such as potassium nitrate.
Section 6: Accidental Release Measures
Spill Procedures Protect against identified hazards through use of prescribed personal protection equipment, proper work and hygiene practices. Limit foot and vehicular traffic to minimize mechanical agitation and dispersion. Employ a vacuum, equipped with HEPA (High Efficiency Particulate Air) filter, for clean-up of the spill material. If no vacuum is available, use a broom and shovel to collect excess powder in the area. Residual material should then be cleared, utilizing the process of wet sweeping, to avoid dust generation.
Containment Techniques This is a solid material and will not travel far from the spill location unless mechanically agitated. Therefore, no specific containment techniques are recommended outside of restricting access to the spill location. Arsenic sulfide is considered a hazardous material. During spill cleanup, residual wash waters should be contained and collected for proper disposal. Precautionary measures should be exercised to prevent this substance or associated wash waters from entering the waterways.
Spill Response Equipment The following equipment is recommended for spill response:
• vacuum, equipped with a HEPA filter
• broom, wet mop
• dustpan, shovel, or scoop
• bags, drums, or sacks for collection

Note: Non-sparking equipment may be selected, based on location specific requirements and individual work site evaluations.
Personal Protective Equipment Employees should utilize the following protective equipment when performing spill response activities:
• gloves (neoprene)
• cotton or Tyvek coveralls
• chemical/safety impact goggles
• respiratory equipment recommended in Section 8
Section 7: Handling and Storage
Handling When handling this product, all personnel are directed to:
• Wear all specified elements of PPE, as directed by this document, or under location specific requirements, whichever is more conservative.
• Avoid creating dust, where possible.
Storage The following information provides the appropriate and recommended methods for safe storage and maintenance of product integrity:
• Store in a cool, dry, well-ventilated area.
• Product containers (paper bags, nylon bags, drums, etc.) are prone to physical damage. Care should be taken in storage and handling in order to prevent damage.
• Avoid contact with oxidizers and chemically active metals, since violent reactions may occur.
Section 8: Exposure Controls / Personal Protection
Engineering Controls If user operations generate dusts or fumes, use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. Keep under dry atmosphere. Mechanical exhaust is not recommended. Where any employee is exposed to arsenic above the permissible limits for more than 30 days per year, the employer shall implement engineering and work practice controls including administrative controls to reduce and maintain employee exposure to arsenic in accordance with the implementation schedule specified in 29 CFR 1910.1025(e)(1), except to the extent that the employer can demonstrate that such controls are not feasible. Wherever the engineering and work practice controls which can be instituted are not sufficient to reduce employee exposure to or below the permissible exposure limit, the employer shall nonetheless use them to reduce exposure to the lowest feasible level and shall supplement them by the use of respiratory protection which complies with the requirements of 29 CFR 1910.1025(f).
Respiratory Protection Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Hand Protection Neoprene gloves and full body cotton coveralls are recommended to prevent direct skin contact.

Note: Protective clothing is required if the arsenic exposure exceeds the PEL or TLV. Full body, cotton or disposable coveralls should be worn during use and handling, be left at the work site and be properly disposed of or laundered after use, with the wash water disposed of in accordance with local, state and federal regulations. Personal clothing should be protected from contamination.

Other: An emergency eye wash is recommended in the work area to offer first aid assistance for incidental contact with eyes. All emergency eye wash stations should, at a minimum, meet requirements as established under ANSI Z.358.1 (latest version) for location, design, and operation.
Eye/Face Protection Chemical/safety impact goggles are recommended to be used where excessive dust concentrations may exist. In situations where respiratory protection is required to be used for excessive dust concentrations, a full-face APR may be used in place of a half-face APR with chemical/safety impact goggles.
Work Hygiene Practices To control potential exposures, avoid creating dust. Always wear appropriate protective equipment when handling arsenic compounds. To avoid skin contact, gloves (neoprene) should be worn when handling containers of arsenic compounds. Do not eat, drink, smoke or apply cosmetics while using/handling arsenic compounds. Always wash hands and face after handling arsenic compounds.
• Avoid direct skin contact when possible.
• Do not eat, drink, smoke, or perform other hand-to-mouth activities in product use or handling area.
• Wash thoroughly after handling this product.
Section 9: Physical and Chemical Properties
Appearance Physical State: Solid
Color: Bright Red/Orange
Form: Powder
Odor Odorless
Molecular Weight 246.02
Ph Value Not applicable
Boiling Point (at 760 mm Hg) 565° C. (1049° F.)
Melting Point 355° C. (671° F.) (decomposes)
Flash Point Not applicable
Flammability Not applicable
Autoignition Temperature Not applicable
Explosive Properties Not applicable
Explosion Limits Not applicable
Vapor Pressure (mm Hg) No data
Vapor Density (Air=1) No data
Solubility Very slightly soluble, reacts
Specific Gravity (Water=1) 3.43
Viscosity Not applicable.
Evaporation Rate (BuAc=1) Not applicable
Apparent Density No data
Section 10: Stability and Reactivity
Stability Stable under ordinary conditions of use and storage. Stable to 355° C. (671° F.).
Hazardous Decomposition Products Arsenic gas and hydrogen sulfide.
Hazardous Polymerization Will not occur.
Incompatibilities Reacts with hydrogen peroxide and other strong oxidizers to liberate hydrogen gas. Do not heat in the presence of potassium metal.
Conditions to Avoid Incompatible materials, moisture and excessive temperatures.
Section 11: Toxicological Information
Occupationally Relevant Routes of Exposure
Inhalation No quantitative information found.
Ingestion Mouse, LD50: 254 mg/kg
Rat, LD50: 185 mg/kg
Skin Rat, LD50: 936 mg/kg
Rat, LD50: 185 mg/kg
Eye No quantitative information found.
Other Arsenic is highly toxic when ingested and is carcinogenic. Tumorigenic.
OSHA Regulated: Yes
ACGIH: A1 - Confirmed Human Carcinogen (listed as "Arsenic, inorganic compounds").
California: Carcinogen, initial date 2/27/87 (listed as "Arsenic, inorganic compounds").
NTP: Known carcinogen (listed as "Arsenic, inorganic compounds").
IARC: Group 1 carcinogen
Epidemiology: Exposure to inorganic arsenic compounds in drugs, food, and water as well as in an occupational setting have been causally associated with the development of cancer, primarily of the skin and lungs. IARC has determined that there is sufficient evidence for carcinogenicity for arsenic compounds to humans.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Mutagenicity: No information available.
Neurotoxicity: No information available.
Section 12: Ecological Information
  Arsenic and its compounds have been known as metals since ancient times. It occurs widely in the earth's crust and can be dissolved from rocks and minerals into surface waters. Arsenic and its compounds have a variety of commercial and industrial uses.
Acute (short-term)
Ecological Effects		 Acute toxic effects to excessive concentrations may include death of some animals, birds, or fish, and possible death or low growth rate in some plants. Acute effects are seen two to four days after animals or plants come in contact with a toxic chemical substance. Toxicity to aquatic life is affected by water hardness - the softer the water the greater the toxicity. Arsenic and its compounds have high acute toxicity to aquatic life. Insufficient data are available to evaluate or predict the short-term effects of arsenic and its compounds to plants, birds, or land animals.
Chronic (long-term)
Ecological Effects		 No information available.
Water Solubility Arsenic and its compounds range in their respective water solubilities from soluble to practically insoluble.
Distribution and Persistence
in the Environment		 No information available.
Bioaccumulation in
Aquatic Organisms		 No information available.
Permissible Concentration
in Water		 No information available.
Section 13: Disposal Considerations
Physical/Chemical Properties This material is a stable solid.
Recommended Disposal Method Where possible, re-blend spilled, unused, or off-specification materials with other suitable materials in support of waste minimization. Where this is not possible, dispose of material according to Federal (country-specific), state, and local requirements.
Empty Containers This product may be shipped in paper or nylon bags, steel drums, plastic or steel pails, or intermediate bulk containers. All residual material must be emptied and the containers recycled where possible. Where recycling is not possible, containers must be disposed of in accordance with Federal (country-specific), state, and local regulations. If questions exist about disposal, please contact the manufacturer for additional information.
Section 14: Transportation Information
Shipping Name ARSENIC COMPOUNDS, SOLID, N.O.S.
DOT Class Poison B
Hazards Class 6.1
UN Number 1557
Packing Group III
Emergency Response Guidebook
Information		 Produced by the US DOT the ERG is designed to aid first responders in quickly identifying specific or generic hazards of materials involved in an incident and protecting themselves and the general public during the initial response phase of an incident.

UN No. Guide Name of Materials ISO H2O React TIH Gas(es)
1557 152 Arsenic trisulfide No No
1557 152 Arsenic trisulphide No No
Section 15: Regulatory Information
SARA 313 Title III The product or component(s) of the product we sell to you is subject to the reporting requirements of Section 313, Title III of the Superfund Amendments and Re-authorization Act of 1986 (SARA), 40 CFR Part 372.

Product Chemical CAS Number % By Weight
Arsenic Sulfide Arsenic Compounds 1303-33-9 0-100
OSHA Status None of the chemicals in this product are considered highly hazardous by OSHA.
TSCA Chemical Inventory CAS No. 1303-33-9 is on the EPA Toxic Substance Control Act (TSCA) inventory List.
Section 12b None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances
and corresponding RQs		 CAS No. 1303-33-9: 1 lb final RQ; 0.454 kg final RQ
SARA Section 302
Extremely Hazardous Substances		 None of the chemicals in this product have a TPQ.
Section 313 This material contains Arsenic(III) sulfide (listed as Arsenic, inorganic compounds), 99.99%, (CAS No. 1303-33-9) which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act CAS No. 1303-33-9 (listed as "Arsenic, inorganic compounds") is listed as a hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act CAS No. 1303-33-9 (listed as "Arsenic, inorganic compounds") is listed as a Hazardous Substance under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. CAS No. 1303-33-9 is listed as a Toxic Pollutant under the Clean Water Act.
State CAS No. 1303-33-9 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota (listed as "Arsenic, inorganic compounds"), Massachusetts.
California Proposition 65 WARNING: This product contains levels of listed substances, which the state of California has found to cause cancer, birth defects or other reproductive effects.
International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols:
T N
Risk Phrases:
R 23/25 Toxic by inhalation and if swallowed.
R 50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Phrases:
S 20/21 When using do not eat, drink or smoke.
S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
S 60 This material and its container must be disposed of as hazardous waste.
S 28A After contact with skin, wash immediately with plenty of water.
S 61 Avoid release to the environment. Refer to special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS No. 1303-33-9: No information available.
Canada - DSL/NDSL
CAS No. 1303-33-9 is listed on Canada's DSL List.
Canadian Ingredient Disclosure List
CAS No. 1303-33-9 is listed on the Canadian Ingredient Disclosure List.
WHMIS This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
Section 16: Labeling Information
Product Name Realgar
Ingredients Arsenic Sulfide
Signal Word Danger!
Hazard Description This product contains inorganic arsenic compounds. When handling contents, do not inhale or swallow. Overexposure through inhalation and/or ingestion could cause damage to the blood or the nervous, digestive, and/or renal systems.
Precautionary
Measures		 Avoid contact with the skin, eyes, and mucous membranes. Use with adequate ventilation. Wear appropriate personal protective equipment. When handling contents, use NIOSH/MSHA approved respirators, clean protective clothing and gloves. Keep out of reach of children. Keep away from feed and food products. Continued exposure without these precautions could arsenic to arsenic poisoning. Wash thoroughly after use.
First aid
Procedures		 Inhalation: Remove victim to fresh air. Restore breathing if necessary. If conscious, have victim clear nasal passages.
Ingestion: If victim is conscious and alert, give 2 to 4 cups of milk or water but DO NOT induce vomiting.
Eyes: Holding eyelids open, gently flush eyes for 15 minutes with large quantities of water. Do not allow the victim to rub their eyes.
Skin: Brush off area and then wash with soap and water.
In all cases of administered first aid, seek medical attention.
Fire Instructions This material is not flammable; however, it may contribute toxic fumes of arsenic if involved in a fire. Select fire extinguishment media for surrounding materials.
Spill or Leak
Procedures		 Wear appropriate protective equipment. Limit foot and vehicular traffic to minimize agitation and dispersion. Employ a vacuum (equipped with a HEPA filter), broom and shovel, and wet sweeping for spill clean-up. Avoid creating dust. Do not allow this product or run-off to reach waterways.
Handling and
Storage Instructions		 Wear specified elements of personal protective equipment, as defined in the Material Safety Data Sheet (MSDS), or follow location specific instructions for handling this product. Store in a cool, dry, well-ventilated area. Specific instructions concerning directions for use and handling may be found in the MSDS or may be supplied by the manufacturer.
Section 17: Other Information
HMIS Ratings Health: 4
Flammability: 0
Reactivity: 2
Personal Protection: X
Date 24 August 2007
Disclaimer The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Natural Pigments, LLC shall not be held liable for any damage resulting from handling or from contact with the above product.

Copyright 2005-2007 Natural Pigments, LLC. License granted to make unlimited paper copies for internal use only.